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Decoding Nioxin System 1 Cleanser: Ingredients, Benefits, and How it Works

Hair loss and thinning can be a significant source of stress and anxiety. Around 1 in 4 people with hereditary male pattern baldness start losing their hair before the age of 21, and by the age of 35, around 2 in 3 experience some degree of hair loss. Over 50% of women experience postmenopause hair loss, according to a recent study. Pregnancy, stress, nutritional deficiencies, medications, and health conditions can also lead to thinning hair. Fortunately, there are products like Nioxin that can help stop hair loss and even promote new hair growth.

What is Nioxin System 1 Cleanser?

Nioxin System 1 Cleanser is a shampoo designed for natural, untreated hair experiencing light thinning. Clinically and dermatologically tested, the shampoo nourishes and gently cleanses the hair to prevent follicle-clogging sebum, resulting in thicker, fuller hair.

Core Benefits of Nioxin System 1 Cleanser

The primary benefit of Nioxin System 1 Cleanser, like other Nioxin products, is addressing hair thinning. Nioxin claims its products reduce hair fall due to breakage by up to 91%, and that 85% of customers who have tried the Nioxin System Kits “noticed a thickening effect” in their hair. The System Kit 1 Shampoo is designed for natural, untreated hair with light thinning.

Featured Ingredients in Nioxin System 1 Cleanser

The shampoo features a blend of ingredients, including wild mint oil, peppermint oil, and salicylic acid. Here's a deeper dive into some key components and their roles:

  • Water (Aqua/Eau): The most common skincare ingredient of all. The water used in cosmetics is purified and deionized.
  • Sodium Laureth Sulfate: A cleansing agent that is considered absolutely ok in the amount used in cosmetic products. The SLES molecule has a bigger water-soluble head part that makes it milder and much less irritating.
  • Sodium Lauryl Sulfate: A cleansing agent known for being effective but potentially irritating to the skin.
  • Cocamidopropyl Betaine: A mild surfactant and foam stabilizer often used in combination with other cleansing agents.
  • Sodium Chloride: The fancy name for salt, acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents.
  • Citric Acid: An AHA that comes from citrus fruits. A little helper ingredient that is used to adjust the pH of the product.
  • Peppermint Oil: The essential oil coming from steam distillation of freshly harvested, flowering peppermint sprigs.
  • Sodium Hydroxide: The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right.
  • Methylparaben: The most common type of parabens. Using a good sunscreen next to MP containing products is a good idea.
  • Propylene Glycol: A common glycol that improves the freeze-thaw stability of products.
  • Green Tea Extract: One of the most researched natural ingredients. The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin).
  • Biotin: Vitamin H is a great supplement for stronger nails and hair.
  • Lecithin: A very common ingredient that can be found in all cell membranes. An emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes.
  • Niacinamide: A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties.
  • Panthenol: Pro-Vitamin B5 is a goodie that moisturises the skin, has anti-inflammatory, skin protecting and wound healing properties.
  • Tocopheryl Acetate: A form of vitamin E that works as an antioxidant.
  • Grapefruit Peel Oil: The essential oil coming from the peel of the pink grapefruit.
  • CI 42090: A super common synthetic colorant in beauty & food.
  • Yeast Extract: Yeast contains beta-glucan that is a great soothing ingredient and also a mild antioxidant.
  • Sugar Maple Extract: The extract coming from the Sugar Maple tree. It contains natural AHA acids, namely Malic and Tartaric, and hence why it supposedly helps slough off dead skin cells.
  • Sugarcane Extract: A handy moisturizing ingredient mostly used as a humectant.
  • Orange Fruit Extract: Orange fruit is loaded with lots of other active compounds with a wide variety of possible effects. Contains mainly citric acid and some malic acid, AHA exfoliants known for their skin renewing properties.
  • Potassium Sorbate: A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast.

How to Use Nioxin System 1 Cleanser

  1. Apply the shampoo to the scalp and gently massage evenly.
  2. Rinse thoroughly.
  3. For best results, follow with the Nioxin System 1 Scalp Therapy Conditioner and Scalp & Hair Treatment.

Nioxin System Kits: A Comprehensive Approach

Nioxin offers supplemental hair care kits called System Kits. These kits are tailored to natural, color-treated, and bleached hair types. Each kit comes in two strengths, one for light hair thinning and one for more progressed thinning. These products replace your shampoo and conditioner, but they don’t contain minoxidil. The idea behind these kits is that they provide the best possible conditions for regrowth.

Read also: Ingredient Analysis: Nioxin Shampoo

The System Kits consist of three products:

  • Scalp Shampoo: Like a traditional shampoo, the Nioxin Scalp Shampoo removes dirt and sebum to cleanse the scalp and prepare it for the next steps.
  • Scalp Conditioner: Using delicate moisturizers, this conditioner is meant to strengthen hair without weighing it down.
  • Scalp & Hair Treatment: This leave-in treatment is meant to be used after towel-drying your hair. It includes nicotinate, a compound made of niacin that research from 2005 shows can increase hair fullness.

Understanding Minoxidil and Nioxin

It's important to distinguish between Nioxin products containing minoxidil and those that don't. Nioxin offers two products for hair loss containing minoxidil: 2% Minoxidil Hair Regrowth Treatment for women and 5% Minoxidil Hair Regrowth Treatment for men. The System Kits, including the System 1 Cleanser, do not contain minoxidil. They are designed to create an optimal environment for hair growth and are often used in conjunction with minoxidil treatments.

Minoxidil has been clinically tested and proven to increase hair regrowth. According to Yadav, the active ingredient in Nioxin, minoxidil (which is also found in hair loss treatments like Rogaine, Keranique, and many others), can stop hair loss in about half of those who use it for androgenic alopecia. “Minoxidil’s efficacy is best for people with male or female pattern hair loss,” Yadav says. “If you have a receding hairline or sparse hair at the front of your scalp, this product may not be as helpful.” She says it’s most effective if used before age 40, because “treating androgenic alopecia as early as possible can often be essential to achieving results.”

Nioxin Hair Regrowth Kit

Nioxin offers a Hair Regrowth Kit that includes the shampoo, the conditioner and the hair regrowth treatment (the formula that contains minoxidil). You can choose from a kit with the 2% or 5% minoxidil formula. This is a great option for maintaining the quality of your hair while also getting the proven benefits of minoxidil. Plus, it gives you the most bang for your buck.

Starting a Nioxin Regimen

  1. Determine which products are right for you: Use the hair regrowth treatment, which contains minoxidil, on its own or in conjunction with a System Kit. The brand suggests using the treatment with its shampoo and conditioner for optimal results. You can talk with your dermatologist for additional guidance on a treatment plan.
  2. Apply products according to the directions: Whether you use just the minoxidil hair regrowth treatment or the treatment with one of the three-step System Kits, it’s important to use the products as directed and continue to use them daily. If you use both the treatment and the kit daily, know that the hair regrowth treatment should be applied to a dry scalp. You should not wet your scalp for at least 4 hours after application.
  3. Be consistent and patient: According to Yadav, a number of people give up on products like Nioxin, because they don’t see results fast enough. “Consistency is key for any treatment, because hair can only grow about 1 centimeter a month,” she says. Use the products daily for at least 3 months, so you can determine if it’s really working for you or not.

Understanding How Minoxidil Works

Minoxidil was originally used in the early 1970s as a treatment for high blood pressure. Then doctors began to notice that one of the side effects was hair regrowth in balding people. At that point, scientists began developing topical scalp hair regrowth treatments.

Read also: Fact vs. Fiction: Nioxin Shampoo

Even though these products have been used successfully for years, scientists still only have a limited understanding of how minoxidil stimulates hair growth. Studies of topical minoxidil suggest that it shortens the telogen (resting) phase of hair, which prompts the follicles to enter the anagen (growing) phase. It seems that minoxidil prolongs the anagen phase and boosts hair follicle size.

Considerations When Using Minoxidil

  • Application: You should always apply Nioxin hair regrowth treatment to a dry scalp for optimal results. You then need to keep your scalp dry for at least 4 hours to allow the treatment to work. This means no exposure to water, swimming, showering, or even heavy rain. After the 4 hours have elapsed, you can wash your hair.
  • Consistency is Key: If you stop using Nioxin, you’ll likely notice your hair begins to thin once again. The products encourage hair growth and prevent hair loss only when you’re actively using the products as directed.
  • Potential for Systemic Absorption: Yes, in some cases, but absorption through healthy skin is minimal. Nioxin estimates that less than 5% of the topical dose is absorbed from intact skin into the bloodstream.
  • Possible Side Effects: The most common side effects are scalp sensitivity, specifically itching and skin irritation. People also report hair loss initially when starting Nioxin, or any product that contains minoxidil as the active ingredient. This is temporary, as new growth replaces the hair you lose. Some people also report unwanted hair growth when using Nioxin products.

Potential Side Effects

The most common side effects are scalp sensitivity, specifically itching and skin irritation. Gonzalez tells her patients to test a small area before applying product to the larger areas of concern. “Always consult with a dermatologist if irritation becomes severe, as there are ways to manage it,” she says.

People also report hair loss initially when starting Nioxin, or any product that contains minoxidil as the active ingredient. This is temporary, as new growth replaces the hair you lose. Some people also report unwanted hair growth when using Nioxin products. Yadav advises being careful not to get product anywhere on the face for this reason. Rinse immediately if contact occurs.

How Long Does it Take for Nioxin to Work?

According to the brand, 9 out of 10 users notice thicker hair within the first 30 days of using the System Kit. It typically takes 1 to 3 months to see significant hair regrowth from the hair regrowth treatment.

User Reviews and Feedback

The System Kits also get great feedback from people with hair loss and professional stylists. Reviewers rave about their hair’s health, strength, and overall appearance. A stylist shared that this is her go-to product for customers with thinning hair, adding she has “seen almost full heads of hair grow back,” after using them.

Read also: Ingredients for Lash Cleanser

However, not everyone has success with Nioxin. For some people, the hair regrowth wasn’t significant enough to warrant the price, and they note that using it twice a day was cumbersome. A number of negative reviews about both the hair regrowth treatment and the System Kits say that their hair became brittle, with one reviewer adding that “[my hair is] like orange straw growing from my scalp.”

The majority of the reviews, however, are 4 and 5 stars, with the hair regrowth treatment boasting a 5-star rating of 61% for the 5% option and 64% for the 2% strength on Amazon.

Cost of Nioxin Products

The Nioxin Minoxidil Hair Regrowth Treatment is $35. The Hair Regrowth Kit (which contains the hair regrowth treatment) is $49. The cost for the three-product Nioxin System Kit is $45. You can also get a trial size kit with a 1-month supply of the System Kit’s products for $30.

Seeking Professional Advice

Yadav recommends seeking out a board certified dermatologist, who can accurately diagnose the cause of your hair loss. “Other doctors, like general physicians and endocrinologists, can also work with you to determine if there are underlying causes to your hair loss,” she says. “In many cases, hair loss may not have anything to do with your scalp, but [it] could be caused by nutrition, hormonal imbalances, medications, medical conditions, and many more factors.” She advises seeking medical help immediately if you see abnormally large clumps of hair fall when you’re washing your hair or more than 50 to 100 strands a day.

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